We met with Leslie on 3/21 to discuss synthesizing yeast that produces Hops beta acids. Given previous research, this seems very possible.
As we understand it, the process of making humulone is as follows:
Isovaleryl-coA (byproduct of Leucine metabolism) + 3 malonyl coA (present in yeast)
PIVP (3-methyl-1…) + 2 DMAPP [part of Mevalonate pathway]
It seems that researchers, for another reason, have created yeast that produce PIVP.
Our project will focus on the relationship between bees and yeast. Our ideal Beer of the Future creates a self-sustaining ecosystem that is beneficial to both bees and yeast.
How Bees and Yeast can create a circular economy:
- Our synthesized yeast creates hops beta acids that kill varroa mites (a major factor in colony collapse disorder).These acids are extracted to protect the hives.
- The yeast feeds off the honey produced by the bee hives.
This fermented liquid, flavored with both honey and the hops acids inherent in the yeast, is sold for human consumption. This provides a steady flow of funding for the colony.
- The “used” yeast is fed to the bees as a pollen supplement. This is already a common practice in beekeeping.
March 10 – Begin brewing beer
March 25 – Add honey to beer
Begin brewing mead
March 29 – Confirming w/ Leslie re Yeast
Conceptual Flow & Design [how will this work?]
April 5 – Design
Beer is ready!!
April 12 – Build with Chester/Kadallah
April 19 – Brew
April 26 – present
How much honey does yeast need?